Indiana entered the season with the most all-time losses in FBS history with 714 losses, but by going undefeated they no longer hold that dubious distinction.
Which program replaced Indiana and now has the most all-time losses with 717 losses? Is it Northwestern, Kansas State, Kansas, Rutgers or Duke?
Answer: Northwestern
Here are the top five FBS programs with the most all-time losses as of January 2026:
- Northwestern Wildcats: 717 losses
- Indiana Hoosiers: 714 losses
- Rutgers Scarlet Knights: 708 losses
- Wake Forest Demon Deacons: 698 losses
- Kansas Jayhawks: 686 losses